Scientific Publications

2017

Exploring the Experiences of Women and Health Care Workers in the Context of PMTCT Option B Plus in Malawi


Cataldo, Fabian; Chiwaula, Levison; Nkhata, Misheck; van Lettow, Monique; Kasende, Florence; Rosenberg, Nora E.; Tweya, Hannock; Sampathkumar, Veena; Hosseinipour, Mina; Schouten, Erik; Kapito-Tembo, Atupele; Eliya, Michael; Chimbwandira, Frank; Phiri, Sam; for the PURE Malawi Consortium. JAIDS Journal of Acquired Immune Deficiency Syndromes: 15 April 2017 – Volume 74 – Issue 5 – p 517–522 doi: 10.1097/QAI.0000000000001273 Read more

2016

Shifting human resources for health in the context of ART provision: qualitative and quantitative findings from the Lablite baseline study


Misheck J. Nkhata, Margaret Muzambi, Deborah Ford, Adrienne K. Chan, George Abongomera, Harriet Namata, Ivan Mambule, Annabelle South, Paul Revill, Caroline Grundy, Travor Mabugu, Levison Chiwaula, James Hakim, Cissy Kityo, Andrew Reid, Elly Katabira, Sumeet Sodhi, Charles F. Gilks, Diana M. Gibb, Janet Seeley, Fabian Cataldo and the Lablite team. BMC Health Services Research. 2016; 16:660. DOI: 10.1186/s12913-016-1891-7 Read more

Adherence to Antiretroviral Therapy During and After Pregnancy: Cohort Study on Women Receiving Care in Malawi’s “Option B+” programme


Haas AD,1 Malango T. Msukwa, Egger M, Tenthani L,Tweya H, Jahn A, Gadabu OJ,Tal K, Salazar-Vizcaya L, Estill J,Spoerri A, Phiri N,Chimbwandira F, van Oosterhout JJ, Keiser O. http://cid.oxfordjournals.org/content/early/2016/07/25/cid.ciw500 Read more

Survival functions for defining a clinical management Lost To Follow-Up (LTFU) cut-off in Antiretroviral Therapy (ART) program in Zomba, Malawi


Rachlis B, Cole DC, van Lettow M, Escobar M. BMC Medical Informatics and Decision Making. 2016 May 5;16(1):52. DOI: 10.1186/s12911-016-0290-7 Read more

Neurocognitive Function at the First-Line Failure and on the Second-Line Antiretroviral Therapy in Africa: Analyses From the EARNEST Trial


Andrew Kambugu, Jennifer Thompson, James Hakim, Dinah Tumukunde, Joep J. van Oosterhout, Raymond Mwebaze, Anne Hoppe, James Abach, Charles Kwobah, Alejandro Arenas-Pinto, Sarah A. Walker, Nicholas I. Paton. Journal of Acquired Immune Deficiency Syndromes. 2016;71:506-513 DOI: 10.1097/QAI.0000000000000898 Read more

Same day integration of HIV diagnosis and treatment with antenatal care affects retention in Option B+ Prevention of Mother to Child Transmission services in Zomba District, Malawi


Chan AK, Kanike E, Bedell R, Mayuni I, Manyera R, Mlotha W, Harries AD, van Lettow M. Journal of the International AIDS Society 2016; 19:20672 Read more

Retention in care during the first 3 years of antiretroviral therapy for women in Malawi’s option B+ programme: an observational cohort study


Andreas D Haas, Lyson Tenthani, Malango T Msukwa, Kali Tal, Andreas Jahn, Oliver J Gadabu, Adrian Spoerri, Frank Chimbwandira, Joep van Oosterhout, Olivia Keiser. The Lancet HIV. 2016;3(4):175-182. DOI: 10.1016/S2352-3018(16)00008-4 Read more

Low- and middle-income countries face many common barriers to implementation of maternal health evidence products


Puchalski Ritchie LM, Khan S, Moore JE, Timmings C, van Lettow M, Vogel JP, Mbaruku G, Mrisho M, Mugerwa K, Uka S, Imezoglu AM, Straus SE. Journal of Clinical Epidemiology. 2016 Feb 27. DOI: 10.1016/j.jclinepi.2016.02.017 Read more

The impact of a knowledge translation intervention employing educational outreach and a point-of-care reminder tool vs standard lay health worker training on tuberculosis treatment completion rates: study protocol for a cluster randomized controlled trial


Puchalski-Ritchie LM, van Lettow M, Makwakwa A, Chan AK, Hamid JS, Kawonga H, Martiniuk ALC, Schull MJ, van Schoor V, Zwarensten M, Barnsley J, Straus SE. Read more

The crucial importance of long term follow up for EBOLA virus survivors


Fowler R, Mishra S, Chan A.K. http://dx.doi.org/10.1016/S1473-3099(16)30060-3 DOI: 10.1016/S1473-3099(16)30122-0) Read more

TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial


Laurens Matthew B, Mungwira Randy  G, Nyirenda Osward M, Divala Titus H, Kanjala Maxwell, Muwalo Francis, Mkandawire Felix A, Tsirizani Lufina, Nyangulu Wongani, Mwinjiwa Edson, Taylor Terrie  E. Mallewa Jane, Blackwelder William  C, Plowe Christopher V, Laufer Miriam   K,  van Oosterhout JJ. DOI 10.1186/s13063-016-1392-3 Read more

Characteristics and outcomes of women initiating ART during pregnancy versus breastfeeeding in Option B+ in Malawi


Landes M, Sodhi S, Matengeni A, Meaney C, van Lettow M, Chan AK, van Oosterhout JJ. BMC Public Health 2016 16:713. doi: 10.1186/s12889-016-3380-7. Read more

The value of informal care in the context of Option B+ in Malawi: a contingent valuation approach


Chiwaula L.S, Chirwa G.C, Caltado F, Tembo A.T, van Lettow M, Tweya H, Kayoyo V, Kaunda B, K, Trapence C, Gugsa S, Rosernberg N, Eliya M, Phiri S, Hosseinipour M.C, Kasende F and for the PURE Consortium. DOI 10.1186/s12913-016-1381-y Read more

Adjunctive Steroids in HIV-Associated Cryptococcal Meningitis: A Randomized Controlled Trial in African and Southeast Asian Countries


Beardsley J, Wolbers M, Kibengo FM, Kamali A, Cuc NTK, Binh TQ Chau NVV, Farrar J, Merson L, Phuong L, Thwaites G, Kinh NV, Thuy PT, Chierakul W, Siriboon S, Thiansukhon E, Onsanit S, Supphamongkholchaikul W, Konpan P, Semran K, Chan AK, Heyderman R, Miwnjiwa E, van Oosterhout JJ, Imran D, Basri H, Mayxay M, Dance D, Phimmasone P, Rattanavong S, Lallo DG, Day JN on behalf of CryptoDex Investigators. New England Journal of Medicine 2016; 374:542-54. PMID: 26863355. doi: 10.1056/NEJMoa1509024 Read more

A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children


Schipani A, Pertinez H, Mlota R, Molyneux E, Lopez N, Dzinjalamala FK, van Oosterhout JJ, Ward SA, Khoo S, Davies G. Br J Clin Pharmacol, 2015, DOI: 10.1111/bcp.12848 Read more

Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study


John G Mattis, MBBS, Mathew J Vandy, MBBS, Joyce C Chang, RN, Devin E Platt, BSN, Kerry Dierberg, MD, Daniel G Bausch, MD, Tim Brooks, MBChir, Sampha Conteh, NDSW, Ian Crozier, MD, Robert A Fowler, MDCM, Amadu P Kamara, CON, Cindy Kang, PA, Srividya Mahadevan, MPH, Yealie Mansaray, CON, Lauren Marcell, BA, Gillian McKay, MScPH, Tim O’Dempsey, MRCP, Victoria Parris, MRCP, Ruxandra Pinto, PhD, Audrey Rangel, MPH, Alex P Salam, MBChB, Jessica Shantha, MD, Vanessa Wolfman, MD, Steven Yeh, MD, Adrienne K Chan, MD, Dr Sharmistha Mishra, MD. Lancet Infect Dis. 2015;16(3):331-338. DOI: 10.1016/S1473-3099(15)00489-2 Read more

Same day HIV diagnosis and antiretroviral therapy initiation affects retention in Option B+ prevention of mother-to-child transmission services at antenatal care in Zomba District, Malawi


Chan AK, Kanike E, Bedell R, Mayuni I, Manyera R, Mlotha W, Harries AD, van Lettow M. Journal of the International AIDS Society 2016; 19:20672. Read more

Lay Health Workers experience of a tailored knowledge translation intervention to improve job skills and knowledge: a qualitative study in Zomba district Malawi


Lisa M. Puchalski Ritchie, Monique van Lettow, Jan Barnsley, Adrienne K. Chan, Michael J. Schull, Alexandra L. C. Martiniuk, Austine Makwakwa, Merrick Zwarenstein. BMC medical education. 2016;16:54. DOI: 10.1186/s12909-016-0580-x Read more

Mapping the use of research to support strategies tackling maternal and child health inequities: evidence from six countries in Africa and Latin America


Vargas E, Montekio V.B, Gonzalez-Block M.A, Akweongo P, Hazel Cynthia N. A., Cuembelo M, Limbani F, Bernardo W, Muñoz F. Health Research Policy and Systems 2016, 14:1  DOI:10.1186/s12961-015-0072-1 Read more

2015

Building a knowledge translation platform in Malawi to support evidence-informed health policy.


Berman J, Mitambo C, Matanje-Mwagomba B, Khan S, Kachimanga C, Wroe E, Mwape L, van Oosterhout JJ, Chindebvu G, van Schoor V, van Oosterhout J, Puchalski L, Ulysses P, Kathyola D. Health Research Policy and Systems. 2015;13:73. DOI: 10.1186/s12961-015-0061-4 Read more

Outcomes and Diagnostic Processes in Outpatients with Presumptive Tuberculosis in Zomba District, Malawi.


van Lettow M, Bedell R, Maosa S, Phiri K, Chan AK, Mwinjiwa E, Kwekwesa A, Kawonga H, Joshua M, Harries AD, van Oosterhout JJ. PLoS One. 2015 Nov 10;10(11). DOI: 10;10(11):e0141414 Read more

Breast enlargement in Malawian males on the standard first line antiretroviral therapy regimen: Case reports and review of the literature.


Kwekwesa A , Kandionamaso C, Winata N, Mwinjiwa E, Joshua M, Garone D, Bedell R,van Oosterhout JJ. Malawi Medical Journal; 27(3): 115-117 September 2015. DOI: 10.4314/mmj.v27i3.11 Read more

The effectiveness of interventions to improve uptake and retention of HIV-infected pregnant and breastfeeding women and their infants in prevention of mother to child transmission care programs in low and middle income countries: Protocol for a systematic review and meta-analysis.


Puchalski Ritchie Lisa M, van Lettow Monique, Hosseinipour Mina C , Rosenberg Nora E , Phiri Sam , Landes Megan , Cataldo Fabian, Straus Sharon E. Journal of the Systematic Review 2015 Nov 3;4:144; MS: 1495087327175164 DOI: 10.1186/s13643-015-0136-x Read more

Population level usage of health services, and HIV testing and care, prior to decentralization of antiretroviral therapy in Agago District in rural Northern Uganda


G. Abongomera, S. Kiwuwa-Muyingo, P. Revill, L. Chiwaula, T. Mabugu, A. Phillips, E. Katabira, V. Musiime, C. Gilks, A. Chan, J. Hakim, R. Colebunders ,C. Kityo, D. M. Gibb, J. Seeley, D. Ford13 and for the Lablite Project Team. BMC Health Services Research 2015, 15:527 DOI: 10.1186/s12913-015-1194-4. Read more

A knowledge translation intervention to improve tuberculosis care and outcomes in Malawi: a pragmatic cluster randomized controlled trial.


Puchalski Ritchie LM, Schull MJ, Martiniuk ALC, Barnsley J, Arenovich T, van Lettow M, Chan AK, Mills EH, Makwakwa A, Zwarenstein M. Implementation Science 2015; 10:38 DOI: 10.1186/s13012-015-0228-y Read More

HIV Testing Among Pregnant Women Who Attend Antenatal Care in Malawi.


Tenthani L, MPH, Haas AD, MA, Egger M, MD, MSc, van Oosterhout J, MD, PhD, Jahn A, MD, PhD, Chimbwandira F, MD, MPH, Tal K, PhD, Myer L, PhD, Estill J, PhD and Keiser O, PhD. JAIDS Journal of Acquired Immune Deficiency Syndromes 2015 Aug 15;69(5):610-4. DOI: 10.1097/QAI.0000000000000669 Read More

Clinical Characteristics and Lung Function in Older Children Vertically Infected With Human Immunodeficiency Virus in Malawi


MwalukomoT,  Rylance S.J, Emily L. Webb, Anderson S, O’Hare B, van Oosterhout JJ, Rashida A. Ferrand, Corbett EL, Rylance J.. Journal of the Pediatric Infectious Diseases Society, 2015. DOI:10.1093/jpids/piv045 Read more 

Pharmacokinetics of anti-tuberculosis drugs in HIV-positive and HIV-negative adults in Malawi.


van Oosterhout JJ, Dzinjalamala FK, Dimba A, Waterhouse D, Davies G, Zijlstra EE, Molyneux ME, Molyneux EM, Ward S. Antimicrob Agents Chemother. 2015; pii: AAC.01193-15. Read More

‘Deep down in their heart, they wish they could be given some incentives’: a qualitative study on the changing roles and relations of care among home-based caregivers in Zambia


Fabian Cataldo, Karina Kielmann, Tara Kielmann, Gitau Mburu and Maurice Musheke. BMC Health Services Research, 2015 Jan; 15:36. DOI: 10.1186/s12913-015-0685-7 Read more

2014

CryptoDex: A randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial.


Day J, Imran D, Ganiem AR, Tjahjani N, Wahyuningsih R, Adawiyah R, Dance D, Mayxay M, Newton P, Phetsouvanh R, Rattanavong S, Chan AK, Heyderman R, van Oosterhout JJ, Chierakul W, Day N, Kamali A, Kibengo F, Ruzagira E, Gray A, Lalloo DG, Beardsley J, Binh TQ, Chau TT, Chau NV, Cuc NT, Farrar J, Hien TT, Van Kinh N, Merson L, Phuong L, Tho LT, Thuy PT, Thwaites G, Wertheim H, Wolbers M. Trials 2014 Nov;15:441 DOI: 10.1186/1745-6215-15-441. Read more

CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations.


Carr DF, Chaponda M, Cornejo Castro EM, Jorgensen AL, Khoo S, Van Oosterhout JJ, Dandara C, Kampira E, Ssali F, Munderi P, Lalloo DG, Heyderman RS, Pirmohamed M. J Antimicrob Chemother. 2014 Nov;69(12):3329-34. DOI: 10.1093/jac/dku315. Read more

Hepatitis B virus (HBV) sub-genotype A1 infection is characterized by high replication levels and rapid emergence of drug resistance in HIV-positive adults receiving first-line antiretroviral therapy (ART) in Malawi.


Aoudjane S, Chaponda M, González Del Castillo AA, O’Connor J, Noguera M, Beloukas A, Hopkins M, Khoo S, van Oosterhout J, Geretti AM. Clin Infect Dis. 2014 Nov; 59(11):1618-26. DOI: 10.1093/cid/ciu630. Read more

Improving PMTCT Uptake and Retention Services Through Novel Approaches in Peer-Based Family-Supported Care in the Clinic and Community: A 3-Arm Cluster Randomized Trial (PURE Malawi).


Rosenberg NE, van Lettow M, Tweya H, Kapito-Tembo A, Bourdon CM, Cataldo F, Chiwaula L, Sampathkumar V, Trapence C, Kayoyo V, Kasende F, Kaunda B, Speight C, Schouten E, Eliya M, Hosseinipour M, Phiri S; PURE Malawi Consortium. J Acquir Immune Defic Syndr. 2014 Nov 1;67 Suppl 2:S114-9. Read more

Effect of optional home initiation of HIV care following HIV self-testing on antiretroviral therapy initiation among adults in Malawi: a randomized clinical trial.


MacPherson P, Lalloo DG, Webb EL, Maheswaran H, Choko AT, Makombe SD, Butterworth AE, van Oosterhout JJ, Desmond N, Thindwa D, Squire SB, Hayes RJ, Corbett EL. JAMA. Aug 1, 2014;312(4):372-9. DOI: 10.1001/jama.2014.6493. Read more

The Lablite project: A cross-sectional mapping survey of decentralized HIV service provision in Malawi, Uganda and Zimbabwe.


Adrienne K Chan, Deborah Ford, Harriet Namata, Margaret Muzambi, Misheck J Nkhata, George Abongomera, Ivan Mambule, Annabelle South, Paul Revill, Caroline Grundy, Travor Mabugu, Levison Chiwaula, Fabian Cataldo, James Hakim, Janet Seeley, Cissy Kityo, Andrew Reid, Elly Katabira, Sumeet Sodhi, Charles F Gilks and Diana M Gibb. BMC Health Services Research, 2014 Aug 19;14:352. DOI: 10.1186/1472-6963-14-352 Read more

Peripheral Blood Mitochondrial DNA/Nuclear DNA (mtDNA/nDNA) Ratio as a Marker of Mitochondrial Toxicities of Stavudine Containing Antiretroviral Therapy in HIV-Infected Malawian Patients.


Kampira E, Dzobo K, Kumwenda J, van Oosterhout JJ, Parker MI, Dandara C. OMICS. 2014 Jul;18(7):438-45. DOI: 10.1089/omi.2014.0026. Read more

Towards elimination of mother-to-child transmission of HIV: performance of different models of care for initiating lifelong antiretroviral therapy for pregnant women in Malawi (Option B+)


Monique van Lettow, Richard Bedell, Isabell Mayuni, Gabriel Mateyu, Megan Landes, Adrienne K Chan, Vanessa van Schoor, Teferi Beyene, Anthony D Harries, Stephen Chu, Andrew Mganga, Joep J van Oosterhout. Journal of the International AIDS Society, 28 July 2014, 17:18994. DOI: 10.7448/IAS.17.1.18994 Read more

Follow-Up Visit Patterns in an Antiretroviral Therapy (ART) Programme in Zomba, Malawi.


Beth Rachlis, Donald C. Cole, Monique van Lettow, Michael Escobar, Adamson S. Muula, Farah Ahmad, James Orbinski, Adrienne K. Chan. PLoS ONE 2014 July 17 9(7): e101875. DOI: 10.1371/journal.pone.0101875 Read more

Incomplete Recovery of Pneumococcal CD4 T Cell Immunity after Initiation of Antiretroviral Therapy in HIV-Infected Malawian Adults.


Sepako E, Glennie SJ, Jambo KC, Mzinza D, Iwajomo OH, Banda D, van Oosterhout JJ, A Williams N, Gordon SB, Heyderman RS. PLoS One Jun 24, 2014; 24;9(6):e100640. Read more

HIV Associated Neurocognitive Disorders (HAND) in Malawian Adults and Effect on Adherence to Combination Anti-Retroviral Therapy: A Cross Sectional Study.


Christine M. Kelly, Joep J. van Oosterhout, Chisomo Ngwalo, Robert C. Stewart, Laura Benjamin, Kevin R. Robertson, Saye Khoo, Theresa J. Allain, Tom Solomon. PLoS ONE 10 Jun 2014 9(6): e98962. DOI: 10.1371/journal.pone.0098962 Read more

Task-shifting and prioritization: a situational analysis examining the role and experiences of community health workers in Malawi.


Sarah Smith, Amber Deveridge, Joshua Berman, Joel Negin, Nwaka Mwambene, Elizabeth Chingaipe, Lisa M Puchalski Ritchie and Alexandra Martiniuk. Human Resources for Health, 12, May 2014 12:24. DOI:10.1186/1478-4491-12-24 Read more

Supporting middle-cadre health care workers in Malawi: lessons learned during implementation of the PALM PLUS package


Sumeet Sodhi, Hastings Banda, Damson Kathyola, Martias Joshua, Faye Richardson, Emmay Mah, Hayley MacGregor, Emmanuel Kanike, Sandy Thompson, Lara Fairall, Eric Bateman, Merrick Zwarenstein and Michael J Schull. BMC Health Services Research 2014, 14(Suppl 1):S8, 12 May 2014. DOI: 10.1186/1472-6963-14-S1-S8 Read more

Adolescent HIV disclosure in Zambia: barriers, facilitators and outcomes.


Gitau Mburu, Ian Hodgson, Sam Kalibala, Choolwe Haamujompa, Fabian Cataldo, Elizabeth D Lowenthal, David Ross. Journal of the International AIDS Society, 17 Mar 2014, 17:18866. DOI: 10.7448/IAS.17.1.18866 Read more

A Reduction in Adult Blood Stream Infection and Case Fatality at a Large African Hospital following Antiretroviral Therapy Roll-Out.


Nicholas A. Feasey, Angela Houston, Mavuto Mukaka, Dan Komrower, Thandie Mwalukomo, Lyson Tenthani, Andreas Jahn, Mike Moore, Remco P. H. Peters, Melita A. Gordon, Dean B. Everett, Neil French, Joep J. van Oosterhout, Theresa J. Allain, Robert S. Heyderman. PLoS ONE 9(3) e92226. DOI: 10.1371/journal.pone.0092226 Read more

Assessment of second-line antiretroviral regimens for HIV Therapy in Africa.


N.I. Paton, C. Kityo, A. Hoppe, A. Reid, A. Kambugu, A. Lugemwa, J.J. van Oosterhout, M. Kiconco, A. Siika, R. Mwebaze, M. Abwola, G. Abongomera, A. Mweemba, H. Alima, D. Atwongyeire, R. Nyirenda, J. Boles, J. Thompson, D. Tumukunde, E. Chidziva, I.Mambule, J.R. Arribas, P.J. Easterbrook, J. Hakim, A.S. Walker, P. Mugyeni, EARNEST Trial Team. New England Journal of Medicine 2014 Jul 17;371(3):234-47. DOI: 10.1056/NEJMoa1311274 Read more

Retention in care under universal antiretroviral therapy for HIV-infected pregnant and breastfeeding women (‘Option B+’) in Malawi.


Tenthani L, Haas AD, Tweya H, Jahn A, van Oosterhout JJ, Chimbwandira F, Chirwa Z, Ng’ambi W, Bakali A, Phiri S, Myer L, Valeri F, Zwahlen M, Wandeler G, Keiser O; Ministry of Health in Malawi and IeDEA Southern Africa. AIDS 2014 Feb 20;28(4):589-98. DOI: 10.1097/QAD. 0000000000000143 Read more

Population Pharmacokinetic and Pharmacogenetic Analysis of Nevirapine in Hypersensitive and Tolerant HIV-Infected Patients from Malawi.


Dickinson L, Chaponda M, Carr DF, van Oosterhout JJ, Kumwenda J, Lalloo DG, Pirmohamed M, Heyderman RS, Khoo SH. Antimicrob Agents Chemother. 2014; DOI: 10.1128/AAC.02069-13. Read more

2013

Mitochondrial subhaplogroups and differential risk of stavudine-induced lipodystrophy in Malawian HIV/AIDS patients.


Kampira E, Kumwenda J, Van Oosterhout JJ, Dandara C. Pharmacogenomics 2013; 14 (16):1999-2004. DOI: 10.2217/pgs.13.188 Read more

Women’s attitudes to HIV testing, disclosure and the involvement of male partners in a rural district of Malawi with high HIV prevalence.


Bedell RA, van Lettow M, Landes M. AIDS Care: Psychological and Socio-medical Aspects of AIDS/HIV, 04 Oct 2013;26(4):483-486. DOI: 10.1080/09540121.2013.841830 Read more

Building a National Direction for Research in the Prevention of Mother to Child Transmission of HIV: Results from a national prioritization initiative in Malawi.


Landes M, van Lettow M, Cataldo F, Chan AK, Tippett Barr B, Harries AD, and Bedell R. Health Research Policy and Systems 2013; 11:40. DOI: 10.1186/1478-4505-11-40. Read more

Village registers for vital registration in rural Malawi.


Singogo E, Kanike E, Lutepo T, Phiri H, Assefa B, van Lettow M, Cataldo F, Zachariah R, Bissell K, Harries AD. Tropical Medicine & International Health Aug 2013;18(8):1021-4. DOI: 10.1111/tmi.12132. Read more

Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities.


Chagoma N, Mallewa J, Kaunda S, Njalale Y, Kampira E, Mukaka M, Heyderman RS, and Oosterhout JJ van. C Trans R Soc Trop Med Hyg 2013; 107: 615–619. DOI: 10.1093/trstmh/trt074 Read more

Severe toxicity and polymerase-c gene abnormalities in Malawian adults on stavudine-based antiretroviral therapy.


van Oosterhout, Joep J.; Gardner, Kristiane; Mallewa, Janea; Kaunda, Symona; Kampira, Elizabethc; Payne, Brendane; Heyderman, Robert S.; Chinnery, Patrick. Pharmacogenetics and Genomics, Nov 2013;23(11):624-626. DOI: 10.1097/FPC.0b013e3283655053 Read more

Burden, Characteristics, Management and Outcomes of HIV-infected patients with Kaposi’s sarcoma in Zomba, Malawi.


Mwinjiwa E, Isaakidis P, Van Den Bergh R, Harries AD, Bezanson K, Thompson C, Joshua M, Akello H, Beyene T, van Lettow M. Public Health Action 2013 (3) 2: 180-185(6). DOI: 10.5588/pha.13.0003 Read more

Updating a database of patient level ART data covering multiple and remote facilities in Zomba District, Malawi.


Argarwal M, Bourgeois J, Matengeni A, Bezanson K, van Schoor V, van Lettow M. Public Health Action 21 June 2013:3(2):175-179(5). DOI: 10.5588/pha.12.0096 Read more

Using concept mapping to explore patient defaulting from an antiretroviral therapy program in the Zomba District of Malawi.


Rachlis B, Ahmad F, van Lettow M, Muula AS, Semba M, Cole DC. BMC Health Services Research 2013: 13:210. DOI: 10.1186/1472-6963-13-210. Read more

A taxonomy for community-based care programs focused on HIV/AIDS prevention, treatment, and care in resource-poor settings.


Rachlis B, Sodhi S, Burciul B, Orbinski J, Cheng A, Cole D. Global Health Action, North America, 16 Apr 2013. DOI: 10.3402/gha.v6i0.20548 Read more

Patient costs associated with accessing HIV/AIDS care in Malawi.


Pinto A, van Lettow M, Rachilis B, Chan A, Sodhi S. Journal of the International AIDS Society, North America, 19 Mar 2013. DOI: 10.7448/IAS/16.1.18055 Read more

2012

Mortality and health outcomes of HIV-exposed and unexposed children in a PMTCT cohort in Malawi


Landes M, van Lettow M, Chan AK, Mayuni I, Schouten EJ, and Bedell RA. PLoS ONE 7(10): e47337. DOI: 10.1371/journal.pone.0047337. Read more

Understanding the linkages between informal and formal care for People Living with HIV in Sub-Saharan Africa.


Lees S, Kielmann K, Cataldo F, Gitau-Mburu D. Global Public Health: An International Journal for Research, Policy and Practice, 2012;7(10):1109-19. DOI: 10.1080/17441692.2012.733403. Read more

Six-month mortality among HIV-infected adults presenting for antiretroviral therapy with unexplained weight loss, chronic fever or chronic diarrhea in Malawi.


van Lettow M , Åkesson A, Martiniuk ALC, Ramsay A, Chan AK, Anderson ST, Harries AD, Corbett E, Heyderman RS, Zachariah R, Bedell RA, PLoS ONE 19 Nov 2012;7(11)e48856. DOI: 10.1371/journal.pone.0048856 Read more

High prevalence of tuberculosis and serious bloodstream infections in individuals presenting for antiretroviral therapy in Malawi.


Bedell R, Anderson S, van Lettow M, Chan AK, Åkesson A, Kumwenda M, Harries AD, Ramsay A. PLoS ONE 7(6): e39347. DOI: 10.1371/journal.pone.0039347. Read more

Evaluation of lay health workers’ needs to effectively support TB treatment adherence in Malawi.


Lisa M. Puchalski Ritchie, Monique van Lettow, Jan Barnsley, Adrienne K. Chan, Martias Joshua, Alexandra L.C. Martiniuk, Michael J. Schull, Merrick Zwarenstein. IJTLD 2012 Nov;16(11):1492-7. DOI: 10.5588/ijtld.12.0206 Read more

Involving Expert Patients in Anti-Retroviral Treatment Provision in a Tertiary Referral Hospital HIV Clinic in Malawi


Tenthani L, Cataldo F, Chan AK, Bedell R, Martiniuk A, and van lettow M. BMC Health Services Research, 8 Jun 2012;12:140. DOI: 10.1186/1472-6963-12-140 Read more

Simplified methods of determining treatment retention in Malawi: ART cohort reports vs. Pharmacy stock cards.


Chan AK, Singogo E, Changamire R, Ratsma YEC, Tassie JM, Harries AD. Public Health Action 21 Jun 2012;2(2):32-37(6). DOI: 10.5588/pha.11.0028 Read more

Language in tuberculosis services: can we change to patient-centred terminology and stop the paradigm of blaming the patients?


R. Zachariah, A. D. Harries, S. Srinath, S. Ram, K. Viney, E. Singogo, P. Lal, A. Mendoza-Ticona, A. Sreenivas, N. W. Aung, B. N. Sharath, H. Kanyerere, N. van Soelen, N. Kirui, E. Ali,
S. G. Hinderaker, K. Bissell, D. A. Enarson, M. E. Edginton. International Journal of Tuberculosis and Lung Disease, 2012 Jun;16(6):714-7. DOI: 10.5588/ijtld.11.0635 Read more

Mortality and Health Outcomes in HIV-infected and HIV-uninfected Mothers at 18-20 Months Postpartum in Zomba District, Malawi.


M. Landes, M. van Lettow, R. Bedell, I Mayuni, A.K. Chan, L. Tenthani, E. Schouten. PLoS One 2012 7(9): e44396. DOI: 10.1371/journal.pone.0044396. Read more

2011

Uptake and outcomes of a prevention-of mother-to-child transmission (PMTCT) program in Zomba district, Malawi.


van Lettow M, Bedell R, Landes M, Chan A.K, Gawa L, Gatto S, Mayuni I, Chibuye P, Bisika S. BMC Public Health 2011: 11: 426. Read more

Evaluating a streamlined clinical tool and educational outreach intervention for health care workers in Malawi: The PALM PLUS case study.


Sodhi S, Banda H, Kathyola D, Burciul B, Joshua M, Bateman E, Fairall L, Martiniuk A, Cornick R, Faris G, Draper B, Mondiwa M, Katengeza E, Sanudi L, Zwarenstein M, Schull MJ. BMC Int Health Hum Rights. 2011 Nov 8;11 Suppl 2:S11. Read more

Anti-retroviral treatment outcomes among older adults in Zomba District, Malawi.


Negin J, van Lettow M, Semba M, Martiniuk A, Chan AC, Cumming R. PLoS One. 2011;6(10). Read more

From PALSA PLUS to PALM PLUS: adapting and developing a South African guideline and training intervention to better integrate HIV/AIDS care with primary care in rural health centers in Malawi.


Schull MJ, Cornick R, Thompson S, Faris G, Fairall L, Burciul B, Sodhi S, Draper B, Joshua M, Mondiwa M, Banda H, Kathyola D, Bateman E, Zwarenstein M. Implement Sci. 2011; 6: 82. Read more

Outcome Assessment of a Dedicated HIV Positive Health Care Worker Clinic at a Central Hospital in Malawi: A Retrospective Observational Study.


Chan AK, van Lettow M, Tenthani L, Gawa L, Kadzanja A, Mnthambala A, Kambanji M. PLoS One. 2011;6(5):e19789. Epub 2011 May 19. Read more

Timing and uptake of ART during treatment for active tuberculosis in HIV co-infected adults in Malawi.


van Lettow M, Chan A.K, Ginsburg AS, Thweya H, Gareta D, Njala J, Kanyerere H, Phiri S, Idana I. Public Health Action 2011: 1(1):1-4. Read more

Diagnostic Management and Outcomes of Pulmonary Tuberculosis Suspects admitted to a Central Hospital in Malawi.


Gawa L, Reid ME, Edginton M, van Lettow M, Joshua M, and Harries AD. Public Health Action 2011; 1:1, pp. 2-5(4). Read more

Reasons for accepting or refusing HIV services among TB patients at a TB-HIV integrated clinic in Malawi.


Kumwenda M, Tom S, Chan AK, Mwinjiwa E, Sodhi S, Joshua M, and van Lettow M. Int J Tuberc Lung Dis 2011; 15(12):1663-9. Read more

2010

Strengthening health human resources and improving clinical outcomes through an integrated guideline and educational outreach in resource-poor settings: a cluster-randomized trial.


Schull MJ, Banda H, Kathyola D, Fairall L, Martiniuk A, Burciul B, Zwarenstein M, Sodhi S, Thompson S, Joshua M, Mondiwa M, Bateman E. Trials. 2010 Dec 3;11:118. Read more

Outcome assessment of decentralization of ART provision in a rural district in Malawi using an integrated primary care model.


Chan AK, Mateyu G, Jahn A, Schouten E, Mlotha W, Kambanji M, and van Lettow M. Trop Med Int Health 2010; 15s1:90-97. Read more

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